KKL 顾客使用本产品发表的 0 篇科研文献

Cortagine is a specific corticotropin-releasing factor receptor subtype 1 (CRF1) agonist with an EC₅₀ of 2.6 nM for rCRF1. Cortagine is an anxiolytic and antidepressive agent in the mouse model.

Cortagine inhibits rCRF1 (EC₅₀=0.18 nM) and mCRF_2β (EC₅₀=16 nM) in transfected HEK-293 cells.

Cortagine (30, 100, 300 ng; i.c.v.) significantly decreases the percent time spent in the open arms and number of open arm entries of the elevated plus-maze (EPM) test in nine-week-old male C57BL/6J mice.

Room temperature in continental US; may vary elsewhere.

Sealed storage, away from moisture  
Powder-20°C  2 years   4°C 1 years
*In solvent-80°C 6 months   -20°C 1 month (sealed storage, away from moisture)

DMSO 中的溶解度 : 50 mg/mL (11.26 mM; Need ultrasonic ）