Litorin, an amphibian bombesin peptide derivative, is an bombesin receptor agonist. Litorin stimulates the contraction of smooth muscle, stimulates gastrin, gastric acid, and pancreatic secretion, and suppresses the nutriment in vivo.
体外研究
Tc-Litorin is developed for non-invasive imaging of tumors with overexpressed gastrin-releasing peptide receptors (GRP-R).
[D-Phe,Leu]Litorin inhibits binding of I-[Tyr] BN to murine Swiss 3T3 cells with a Ki of 5.1 nM.
Litorin stimulates H-Thymidine incorporation in murine Swiss 3T3 cells with an EC50 of 2.3 nM.
体内研究
Litorin stimulates the contraction of smooth muscle, stimulates gastrin, gastric acid, and pancreatic secretion, and suppresses the nutriment in in vivo experiments.
分子式
C51H68N14O11S
分子量
1085.24
CAS号
55749-97-8
中文名称
雨滨蛙肽
运输条件
Room temperature in continental US; may vary elsewhere.