Inflammasome Inhibitor 4b
目录号 : KG12989
CAS No. : 2768759-64-2
纯度 : >95%
Inflammasome inhibitor 4b is an inhibitor of NOD-like receptor protein 3 (NLRP3) inflammasome activation. It inhibits ATP-induced IL-1β release by 98.3% in LPS-primed mouse bone marrow-derived macrophages (BMDMs) when used at a concentration of 1 µM. Inflammasome inhibitor 4b (3 and 10 mg/kg) decreases paw swelling and mechanical hyperalgesia in a mouse model of gout induced by monosodium urate crystals.
Other Forms of Rapamycin:
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生物活性 |
Inflammasome inhibitor 4b is an inhibitor of NOD-like receptor protein 3 (NLRP3) inflammasome activation. It inhibits ATP-induced IL-1β release by 98.3% in LPS-primed mouse bone marrow-derived macrophages (BMDMs) when used at a concentration of 1 µM. Inflammasome inhibitor 4b (3 and 10 mg/kg) decreases paw swelling and mechanical hyperalgesia in a mouse model of gout induced by monosodium urate crystals.
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分子式 |
C16H19N2O5S?Na
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分子量 |
374.4
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CAS号 |
2768759-64-2
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运输条件 |
Room temperature in continental US; may vary elsewhere.
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储存方式 |
Store at -20°C
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