TMX-4116 - CAS:2766385-56-0

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TMX-4116

目录号 : KG12926 CAS No. : 2766385-56-0 纯度 : >97%

Data Sheet 产品使用指南

TMX-4116 is a casein kinase 1α (CK1α) degrader. TMX-4116 shows the degradation preference for CK1α with DC50s less than 200 nM in MOLT4, Jurkat, and MM.1S cells. TMX-4116 can be used for the research of multiple myeloma. TMX-4116 (compound 16; 1 μM; 4 h) shows a high degradation preference for CK1α in MOLT4 cells.TMX-4116 (250 nM, 4 h) induces primary target degradation of CK1α, while no downregulation of PDE6D, IKZF1, and IKZF3 in MOLT4 cells.

规格	价格	是否有货	数量
5mg		In-stock
10mg		In-stock

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生物活性	TMX-4116 is a casein kinase 1α (CK1α) degrader. TMX-4116 shows the degradation preference for CK1α with DC50s less than 200 nM in MOLT4, Jurkat, and MM.1S cells. TMX-4116 can be used for the research of multiple myeloma. TMX-4116 (compound 16; 1 μM; 4 h) shows a high degradation preference for CK1α in MOLT4 cells.TMX-4116 (250 nM, 4 h) induces primary target degradation of CK1α, while no downregulation of PDE6D, IKZF1, and IKZF3 in MOLT4 cells.
分子式	C₁₇H₁₉N₅O₄S
分子量	389.43
CAS号	2766385-56-0
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Store at -20°C