(S,R,S)-AHPC TFA (Synonyms:VHL ligand 1 TFA;VH032-NH2 TFA)
目录号 : KE1471 CAS No. : 1631137-51-3 纯度 : ≥95%
(S,R,S)-AHPC TFA (VH032-NH2 TFA) is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC TFA can be connected to the ligand for protein (e.g., BCR-ABL1) by a linker to form PROTACs (e.g., GMB-475). GMB-475 induces the degradation of BCR-ABL1 with an IC50 of 1.11 μM in Ba/F3 cells.
规格 价格 是否有货 数量
50mg
In-stock
100mg
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200mg
In-stock
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生物活性
(S,R,S)-AHPC TFA (VH032-NH2 TFA) is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC TFA can be connected to the ligand for protein (e.g., BCR-ABL1) by a linker to form PROTACs (e.g., GMB-475). GMB-475 induces the degradation of BCR-ABL1 with an IC50 of 1.11 μM in Ba/F3 cells.
分子式
C24H31F3N4O5S
分子量
544.59
CAS号
1631137-51-3
中文名称
VHL ligand 1 TFA;VH032-NH2 TFA
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Store at -20˚C
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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