A-77636 hydrochloride 是一种具有口服活性的、选择性的和长效多巴胺 D1 受体激动剂 (pKi=7.40; Ki=39.8 nM)，具有抗帕金森病活性。A-77636 hydrochloride 对多巴胺 D2 受体无功能活性。
| 生物活性 |
A-77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM) with antiparkinsonian activity. A-77636 hydrochloride is functionally inactive at dopamine D2 receptor. |
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| 体内研究 |
A-77636 (0.1-1 mg/kg) exerts a suppressant effect on food intake, due principally to a reduction in meal size and duration.
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| 分子式 |
C20H27NO3.HCl
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| 分子量 |
365.89
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| CAS号 |
145307-34-2
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
-20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
纯度： ≥98%
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