L-Glutamine-d5 - CAS:14341-78-7

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L-Glutamine-d5 (Synonyms:L-谷氨酰胺-2,3,3,4,4-d5;L-谷氨酰胺-D5;L-谷氨酰胺-D5氘代内标)

目录号 : KG12460 CAS No. : 14341-78-7 纯度 : 98%

产品说明书产品使用指南

L-Glutamine-d5 is intended for use as an internal standard for the quantification of L-glutamine by GC- or LC-MS. L-Glutamine is a non-essential amino acid involved in many biochemical processes. It is synthesized in vivo by glutamate and ammonia. It serves as a substrate for glutamine synthetase in neurons for the biosynthesis of the major excitatory and inhibitory neurotransmitters glutamate and GABA. L-Glutamine decreases adhesion of sickle red blood cells (RBCs) to human umbilical vein endothelial cells (HUVECs) when incubated ex vivo with patient-derived autologous plasma either alone or with LPS. It has commonly been used in cell culture media. Formulations containing L-glutamine have been used in the treatment of sickle cell disease.

规格	是否有货	数量
1mg	In-stock	立即试用
5mg	In-stock
10mg	In-stock
25mg	In-stock

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生物活性

L-Glutamine-d5 (L-Glutamic acid 5-amide-d5) is the deuterium labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells.

体外研究

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

分子式

C₅H₅D₅N₂O₃

分子量

151.2

CAS号

14341-78-7

中文名称

L-谷氨酰胺-D5氘代内标

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

纯度： 98%

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，注：如该浓度超过该批次药物DMSO溶解度，请先联系客服）；

体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL ddH₂O，混匀澄清。

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注意：1. 首先保证母液是澄清的；
2. 一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。

Other Forms of Rapamycin:

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