Luteinizing hormone releasing hormone human acetate salt (LHRH) (Synonyms:戈那瑞林二醋酸盐;醋酸戈那瑞林;醋酸戈那瑞林 Gonadorelin Acetate;醋酸戈那瑞林 GonadorelinAcetate;醋酸戈那瑞林二醋酸盐;戈那瑞林醋酸;戈那瑞林二醋酸盐标准品(JP);戈那瑞林(GONADORELIN);黄体生成素释放激素)
目录号 : KG12138 CAS No. : 71447-49-9 纯度 : 98%
Luteinizing hormone releasing hormone human acetate salt (LHRH) is a selective acitivator of MMP-2 and MMP-9 . Luteinizing hormone-releasing hormone (LHRH), also known as Gonadotropin-releasing hormone (GnRH) is a trophic peptide hormone which secreted by GnRH neurons and plays an important role in the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary . MMP-2 (matrix metalloproteinase-2) and MMP-9 (matrix metalloproteinase-9) belong to the MMP family that play an important role in the breakdown of extracellular matrix (ECM) in normal physiological processes, for example, embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis . When tested with Ishikawa and ECC-1 cell lines, LHRH resulted in the increase of MMP-9 expression which induced cell invasion and it was also showed that GPR101 mediated the LHRH activity and cooperated to function in the metastatic potential of endometrial cancer cells . In human decidual endometrial stromal cells, LHRH with its receptor induced the activation of MMP-2 and MMP-9 .
规格 价格 是否有货 数量
1mg
In-stock
立即试用
5mg
In-stock

Other Forms of Rapamycin:

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分子式
C55H75N17O13
分子量
1182.29
CAS号
71447-49-9
中文名称
戈那瑞林二醋酸盐
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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