SABRAC
目录号 : KG12090
CAS No. : 886212-98-2
纯度 : >95%
SABRAC is an inhibitor of acid ceramidase (IC50 = 52 nM). It is selective for acid ceramidase over neutral ceramidase and the cysteine protease papain at 3 µM. SABRAC inhibits acid ceramidase in PC3 MC metastatic prostate cancer cells (IC50 = <1 µM), as well as induces accumulation of ceramides in the same cells. It completely inhibits anchorage-independent colony formation but does not induce cytotoxicity in PC3 MC cells when used at a concentration of 5 µM.
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| 分子式 |
C20H40BrNO3
|
| 分子量 |
422.4
|
| CAS号 |
886212-98-2
|
| 储存方式 |
-20°C
|
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Data Sheet
