CB-1158
目录号 : KG12079
CAS No. : 1345810-21-0
纯度 : >95%
CB-1158 is an inhibitor of arginase I and II (IC50s = 0.086 and 0.296 µM for the human enzymes, respectively). It is selective for arginase I and II over neuronal nitric oxide synthase (nNOS), endothelial NOS (eNOS), and inducible NOS (iNOS; IC50s = >50 µM for all). CB-1158 reverses inhibition of T cell proliferation induced by granulocytes in vitro (IC50 = 0.204 µM). It reduces tumor growth in a CT26 murine colon cancer model when administered at a dose of 100 mg/kg twice per day.
Other Forms of Rapamycin:
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| 分子式 |
C18H27BCl2N2O4
|
| 分子量 |
417.1
|
| CAS号 |
1345810-21-0
|
| 储存方式 |
-20°C
|
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