16,16-Dimethyl prostaglandin E2 (16,16-dimethyl PGE2) 是一种具有口服活性的脊椎动物造血干细胞 (HSCs) 稳态关键调节剂。16,16-Dimethyl prostaglandin E2 可以通过 EP2/EP4 起作用，并与 Wnt 途径相互作用。
| 生物活性 |
16,16-Dimethyl prostaglandin E2 (16,16-dimethyl PGE2) is an orally active vertebrate Hematopoietic stem cells (HSCs) homeostasis critical regulator. 16,16-Dimethyl prostaglandin E2 can act through EP2/EP4 and has an interaction with the Wnt pathway. |
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| 体内研究 |
16,16-Dimethyl prostaglandin E2 (16,16-dimethyl PGE2; 10 µg/kg; i.p.; every 12 hours; for 8 days) rescues the exacerbated DSS colitis phenotype of Tpl2 mice and restores epithelial proliferation and structure.
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| 分子式 |
C22H36O5
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| 分子量 |
380.52
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| CAS号 |
39746-25-3
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
Solution, -20°C, 2 years |
纯度： ≥98%
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