Thujopsene (Synonyms:(-)-罗汉柏烯;罗汉柏烯;(1S,6S,10S)-2,2,6,9-四甲基三环[8.1.0.01.6]十一烷-8-烯)
目录号 : KG10380 CAS No. : 470-40-6 纯度 : >85%
Thujopsene is a sesquiterpene that has been found in T. dolabrata and has diverse biological activities. It inhibits the Na+/K+-ATPase (IC50 = 25.9 µg/ml) and cytochrome P450 (CYP) isoform CYP2B6 (Ki = 0.8 µM).Thujopsene is active against Gram-positive and Gram-negative bacteria, including S. aureus, M. luteus, and S. typhimurium (MICs = 25-50 µg/ml). It inhibits antigen-induced β-hexosaminidase release from IgE-sensitized RBL-2H3 mast cells (IC50 = 25.1 µM) and is cytotoxic to A549 non-small cell lung cancer (NSCLC) cells with an LC50 value of 35.27 µg/ml. Thujopsene induces mortality in the mites D. farniae and T. putrescentiae (LC50s = 9.82 and 10.92 µg/cm2, respectively).
规格 价格 是否有货 数量
500 µg
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1mg
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分子式
C15H24
分子量
204.4
CAS号
470-40-6
中文名称
(1S,6S,10S)-2,2,6,9-四甲基三环[8.1.0.01.6]十一烷-8-烯
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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