Indium (III) thiosemicarbazone 5b
目录号 : KG10328 CAS No. : 2345755-20-4 纯度 : >95%
Indium (III) thiosemicarbazone 5b is an anticancer agent.It is cytotoxic to A549, MCF-7 breast, MCF-7/DDP cisplatin-resistant breast, and Hl 7702 liver cancer cells (IC50s = 2.41, 1.97, 2.11, and 8.95 µM, respectively). Indium (III) thiosemicarbazone 5b decreases PI3K, Akt, mTOR, P-gp, and GSH levels in MCF-7/DDP cells. In vivo, indium (III) thiosemicarbazone 5b (2.5 µmol/kg) reduces tumor weight and volume in an MCF-7/DDP mouse xenograft model. Liposomes containing indium (III) thiosemicarbazone 5b also induce apoptosis and pro-death autophagy in MCF-7/DDP cells, as well as reduce tumor volume and weight in an MCF-7/DDP mouse xenograft model.
规格 价格 是否有货 数量
1mg
In-stock
立即试用
5mg
In-stock
10mg
In-stock
25mg
In-stock

Other Forms of Rapamycin:

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分子式
C10H15Cl2InN4Os
分子量
425
CAS号
2345755-20-4
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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体内配方配制方法μL DMSO母液,加入 μL PEG300,混匀澄清后加入μL Tween 80,混匀澄清后加入 μL ddH2O,混匀澄清。

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