Complex 3
目录号 : KG10072 CAS No. : 2480150-28-3 纯度 : >90%
Complex 3 is a fluorescent dithiocarbazate-copper complex with anticancer activity.It localizes to mitochondria and displays excitation/emission maxima of 455-495/535 nm, respectively. Complex 3 inhibits the growth of BxPC-3, AsPC-1, PANC-1, and WI38 pancreatic cancer cells (IC50s = 0.74, 0.41, 0.62, and 2.06 µM, respectively). It induces lipid peroxidation and mitochondrial rupture and shrinkage in AsPC-1 cells, effects that can be reduced by the ferroptosis inhibitor liproxstatin-1 . Complex 3 also induces mitochondrial apoptosis and cytokine-cytokine receptor interaction dysfunction in the same cells. In vivo, complex 3 (1.5 and 3 mg/kg) reduces tumor volume and intratumor apoptosis in an AsPC-1 mouse xenograft model.
规格 价格 是否有货 数量
1mg
In-stock
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5mg
In-stock
10mg
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Other Forms of Rapamycin:

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分子式
C26H22Br3Cu3N8S4
分子量
1005.1
CAS号
2480150-28-3
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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