2-Methylthio-AMP diTEA (Synonyms:2-MeSAMP diTEA; 2-Methylthioadenosine 5′-monophosphate diTEA; 2-Methylthioadenosine 5′-phosphate diTEA)
目录号 : KM6579 CAS No. : 1227193-98-7

2-Methylthio-AMP (2-MeSAMP) diTEA 是一种选择性和直接的 P2Y12 拮抗剂。2-Methylthio-AMP diTEA 是 ADP 依赖性血小板聚集的抑制剂。

规格 价格 是否有货 数量
1mg
In-stock
5mg
In-stock

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生物活性

2-Methylthio-AMP (2-MeSAMP) diTEA is a selective and direct P2Y12 antagonist. 2-Methylthio-AMP diTEA is an inhibitor of ADP-dependent platelet aggregation.

体外研究

2-Methylthio-AMP (2-MeSAMP) diTEA inhibits agonist-mediated αIIbβ3 activation in platelets.
2-methylthio-AMP (50 μM; for 5 minutes) diTEA does not significantly inhibit thrombin, PAR1-AP, PAR4-AP, or ADP-mediated platelet Ca mobilization. 2-methylthio-AMP diTEA fails to inhibit Ca mobilization in P2Y12-deficient mouse platelets and does not raise cAMP or induce vasodilator-stimulated phosphoprotein phosphorylation in wild-type platelets.

分子量
595.69
CAS号
1227193-98-7
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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