D-Fructose-1,6-bisphosphate (sodium salt hydrate)
(Synonyms:1,6-二磷酸果糖三钠盐(八水合物);D-果糖-1,6-二磷酸三钠盐,八水合物;D-果糖-1,6-二磷酸三钠盐;D-果糖1,6-二磷酸三钠盐水合物;1,6-二磷酸果糖三钠盐,D-果糖-1,6-二磷酸三钠盐;D-果糖-1,6-二磷酸三钠;D-果糖-1,6-二磷酸三钠,八水;D-果糖-1,6-二磷酸三钠八水合物;D-果糖-1,6-二磷酸三钠盐(FDP),八水;D-果糖-二磷酸三钠盐;果糖二磷酸三钠盐八水合物;甲酰苯胺;磷酸果糖激酶(PFK)测试盒)
D-Fructose-1,6-bisphosphate is an intermediate in carbohydrate metabolism, including glycolysis and gluconeogenesis. During glycolysis, it is generated by the phosphorylation of fructose-6-phosphate by phosphofructokinase. The reverse reaction, mediated by fructose-1,6-bisphosphatase-1, is one of the rate-limiting steps in gluconeogenesis. The same reaction occurs within chloroplasts in plants as part of the reductive pentose phosphate cycle. Because cancer cells adopt glycolysis as a major source of metabolic energy production, this pathway has become a major target for cancer chemotherapy.