(±)-Camphene is a bicyclic monoterpene found in a variety of plants, including Cannabis, that has diverse biological activities, including antiproliferative, pro-apoptotic, hypolipidemic, and insecticidal properties. It inhibits proliferation of B16/F10-Nex2 mouse melanoma, as well as human A2058 melanoma, HL-60 leukemia, U87MG glioblastoma, and SK-BR-3 breast cancer cells (ICs = 71.2, 35.2, 27, 55.4, and 34.7 μg/ml, respectively). (±)-Camphene (70 μg/ml) increases caspase-3 activity and induces apoptosis and endoplasmic reticulum stress in B16/F10-Nex2 cells. It lowers plasma levels of total cholesterol, LDL cholesterol, and triglycerides (TGs) in a Triton WR-1339-induced rat model of hyperlipidemia when administered at a dose of 1.5 μg/g. Dietary administration of (±)-camphene (0.2%) also inhibits hepatic steatosis and insulin resistance in a mouse model of high-fat diet-induced obesity. It also has larvicidal activity against third instar H. armigera larvae (LC = 10.64 μg/ml) and ovicidal activity against H. armigera eggs (EC = 35.39 μg/ml). Formulations containing (±)-camphene have been used as perfume and food additives.