Avilamycin A is an antibiotic. It is active against veterinary isolates of C. perfringens (MICs = ≤0.06-0.5 mg/L) and B. hyodysenteriae (MICs = 12.5-100 μg/ml). Dietary administration of avilamycin A (15 and 30 ppm) reduces mortality in a broiler cockerel model of C. perfringens infection. Formulations containing avilamycin A have been used in the prevention of necrotic enteritis in livestock.