Methiocarb - CAS:2032-65-7

您当前的位置：

Methiocarb (Synonyms:甲硫威; Mercaptodimethur)

目录号 : KCM12409 CAS No. : 2032-65-7 纯度 : ≥98%

Data Sheet SDS 产品使用指南

Methiocarb is a carbamate pesticide with insecticidal, molluscicidal, acaricidal, and bird repellant properties. It inhibits acetylcholinesterase (AChE) activity and is toxic to the western flower thrip (F. occidentalis; IC = 2.1 μM; LC = 3.26 ppm). Methiocarb is also toxic to the land snail M. obstructa (LD = 27.4 μg/snail) and the citrus mite A. pelekassi, inducing 94% mortality when used at a concentration of 0.5 ppm. It reduces the seasonal percentages of cotton bolls infested with pink bollworm (P. gossypiella) to 4%, compared with 65% infestation in untreated controls, when applied to cotton fields at a concentration of 1.86 lb/acre. Methiocarb reduces damage to grapes by song birds when applied to vineyards at a concentration of 2.5 lbs AI per 100 gal water per acre. It is an estrogen receptor α (ERα) and ERβ agonist (ECs = 19.87 and 20.24 μM, respectively) and an androgen receptor antagonist (IC = 13.89 μM) in cell-based reporter assays. It is toxic to juvenile rainbow trout (O. mykiss) and guppies (P. reticulata) with LC values of 0.8 and 1.48 mg/L, respectively, at 48 hours of exposure. Formulations containing methiocarb have been used in the agricultural control of pests.

规格	价格	是否有货	数量
50mg		In-stock
100mg		In-stock

加入购物车大包装询价

Other Forms of Rapamycin:

KKL Med 的所有产品和服务仅用于科学研究，不能被用于人体，兽医，我们也不向个人提供产品和服务。

生物活性

Methiocarb is an orally active carbamate insecticide. Methiocarb exerts dose-dependent toxic effects on onions. In addition to inhibiting acetylcholinesterase to induce cholinergic excitation, Methiocarb can induce lipid peroxidation in liver, kidney, brain and testicular tissues and alter reduced glutathione levels by generating ROS. Methiocarb can be used for agricultural pest control and research on oxidative stress-related cellular damage in mammals.

体外研究

Methiocarb (2.5-7.5 mg/L; 72 hours) has dose-dependent toxic effects on Allium cepa L. bulbs, including reducing rooting rate, root length, and weight gain rate, increasing micronucleus rate, chromosome damage degree, and MDA level, reducing mitotic index, and increasing SOD and CAT activity, with the strongest effect observed at a concentration of 7.5 mg/L.

体内研究

Methiocarb (2-25 mg/kg; i.g.; once/daily; 1-28 days) induces lipid peroxidation and disrupts glutathione levels in the liver, kidneys, brain, and testes of rats.

Animal Model:	Wistar Albino (male, 12-13 weeks old, 160 ± 20 g)
Dosage:	25 mg/kg (1-day treatment); 10 mg/kg (5-day treatment); 2 mg/kg (28-day treatment)
Administration:	i.g.; once (1-day); daily (5-day, 28-day)
Result:	Increased LPO in the liver, kidney, brain and testis after 1, 5 and 28 days treatment, with the most significant increase in the brain. Significantly elevated GSH levels in all the above tissues after 1 day of treatment but significantly decreased after 5 and 28 days of treatment, and the decrease in GSH levels in the kidney, brain and testis was more pronounced than that in the liver.

分子式

C₁₁H₁₅NO₂S

分子量

225.31

CAS号

2032-65-7

中文名称

甲硫威

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

纯度： ≥98%

Data Sheet

SDS

产品使用指南

暂无相关参考文献

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量

浓度

体积

分子量*

重置计算

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度

体积

浓度

体积

重置计算

动物实验计算换算器

第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量）

给药剂量

mg/kg

动物平均体重

每只动物给药体积

动物数量

只

第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系客服为您提供正确的澄清溶液配方）

% DMSO

% Tween 80

% ddH₂O

% DMSO

计算重置

计算结果:

工作液浓度： mg/ml；

DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，注：如该浓度超过该批次药物DMSO溶解度，请先联系客服）；

体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL ddH₂O，混匀澄清。

配置后的溶液总体积：

注意：1. 首先保证母液是澄清的；
2. 一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。

Other Forms of Rapamycin:

KKL 顾客使用本产品发表的 0 篇科研文献

The molarity calculator equation

The dilution calculator equation

动物实验计算换算器