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FzM1
目录号 : KCM11915 CAS No. : 1680196-54-6 纯度 : ≥95%
Data Sheet 产品使用指南
Wnt signaling proteins are small secreted proteins that are active in embryonic development, tissue homeostasis, and tumorigenesis. Wnt proteins initiate cell signaling by binding Frizzled (Fz) receptors, a family of G protein-coupled receptors. FzM1 is an allosteric ligand of Fz4. At 10 µM, it inhibits nuclear translocation of β-catenin in U87MG glioma cells treated with lithium chloride, a GSK3 inhibitor that enhances the Wnt canonical signaling pathway. FzM1 impairs the ability of U87MG cells to form neurospheres in culture and stimulates the differentiation of Caco-2 epithelial colorectal adenocarcinoma cells.
规格 价格 是否有货 数量
500μg
In-stock
1mg
In-stock
5mg
In-stock
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分子式
分子量
360.4
CAS号
1680196-54-6
中文名称
N-[3-hydroxy-5-(2-thienyl)phenyl]-N'-2-naphthalenyl-urea
储存方式
-20°C
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
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The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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