2-(Isopentylamino)naphthalene-1,4-dione is a vitamin K analog. It inhibits spasms induced by pentylenetetrazole (PTZ; ) and tonic hindlimb extension induced by maximal electroshock (MES) in mice (EDs = 349.2 and 108.1 mg/kg, respectively). It also protects mice against seizures in the 6 Hz psychomotor seizure test (EDs = 152.7 and 263.7 mg/kg at stimulus intensities of 32 and 44 mA, respectively).
2-(Isopentylamino)naphthalene-1,4-dione, a Vitamin K analogue, shows protection in Pentylenetetrazole (PTZ)-induced seizure model. 2-(Isopentylamino)naphthalene-1,4-dione significantly increases ATP levels in zebrafish as well as HT-22 cells.2-(Isopentylamino)naphthalene-1,4-dione shows excellent permeability into the brain.
分子式
C15H17NO2
分子量
243.30102
CAS号
1607447-79-9
中文名称
2-(Isopentylamino)naphthalene-1,4-dione
运输条件
Room temperature in continental US; may vary elsewhere.