9-keto Fluprostenol is an analog of prostaglandin E (PGE) with structural modifications intended to give it a prolonged half-life and greater potency. Fluprostenol is a well-studied, potent analog of PGF and acts primarily through the FP receptor. Oxidation at C-9 of fluprostenol yields 9-keto fluprostenol. It is anticipated that this analog will have strong affinity for EP receptors and act as a PGE agonist. However, no studies on the pharmacology of this compound have been published to date.
9-keto Fluprostenol is an analog of prostaglandin E2 (PGE2) with structural modifications intended to give it a prolonged half-life and greater potency. Fluprostenol is a well-studied, potent analog of PGF2α and acts primarily through the FP receptor. Oxidation at C-9 of fluprostenol yields 9-keto fluprostenol. It is anticipated that this analog will have strong affinity for EP receptors and act as a PGE2 agonist.
分子式
C23H27F3O6
分子量
456.45
CAS号
156406-33-6
中文名称
9-酮氟前列醇
运输条件
Room temperature in continental US; may vary elsewhere.