PAF C-16 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the “remodeling” and 'de novo' pathways. It is a potent mediator of neutrophil migration and the production of reactive oxygen species and IL-6. Pathological processes involving PAF include necrotizing enterocolitis, inflammation, asthma, and allergy. PAF C-16 Carboxylic acid is modified with a carboxylic acid group terminating the C-16 alkyl chain. This provides a convenient site for chemical crosslinking.
PAF C-16 carboxylic acid is a phospholipid that possesses haptenic activity causing production of antibodies reactive with platelet-activating factor (PAF).
分子式
C26H52NO9P
分子量
553.7
CAS号
129879-41-0
运输条件
Room temperature in continental US; may vary elsewhere.