CCR1 antagonist 9 is a potent and selective CCR1 antagonist with an IC50 of 6.8 nM in calcium flux assay.
IC50&Target
CCR1
6.8 nM (IC50, in calcium flux assay)
体外研究
CCR1 antagonist 9 (Compound 19e) blocks the CCR1 chemotaxis of THP-1 cells with an IC50 of 28 nM. CCR1 antagonist 9 also blocks hERG with an IC50 of 30 μM.
分子式
C20H16FN5O3S
分子量
425.44
CAS号
1220026-26-5
运输条件
Room temperature in continental US; may vary elsewhere.