(+)-Blebbistatin
(Synonyms:2-溴吲哚)
目录号 : KCM10516
CAS No. : 1177356-70-5
纯度 : ≥98%
(+)-Blebbistatin is the inactive enantiomer of (–)-blebbistatin , which is a selective inhibitor of non-muscle myosin II ATPases. Prolonged exposure to blue light (450-490 nm) results in degradation of blebbistatin to an inactive product via cytotoxic intermediates, which may be problematic for its use in fluorescent live cell imaging applications. (R)-nitro-Blebbistatin is a more stable form of (+)-blebbistatin. The addition of a nitro group stabilizes the molecule to circumvent its degradation by prolonged blue light exposure. (R)-nitro-Blebbistatin has the same stereochemistry as the inactive (+)-blebbistatin enantiomer.
Other Forms of Rapamycin:
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| 分子式 |
C18H16N2O2
|
| 分子量 |
292.3
|
| CAS号 |
1177356-70-5
|
| 中文名称 |
2-溴吲哚
|
| 储存方式 |
-20°C
|
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