BIIL-260 hydrochloride is a potent and long-acting orally active leukotriene B(4) receptor LTB4 antagonist, with anti-inflammatory activity. BIIL-260 hydrochloride interacts with the LTB4 receptor in a saturable, reversible, and competitive manner, has high affinity to the LTB4 receptor on isolated human neutrophil cell membranes with Ki values of 1.7 nM.
体外研究
BIIL-260 hydrochloride potently inhibits LTB4-induced intracellular Ca release in human neutrophils with IC50 value of 0.82 nM
分子式
C30H31ClN2O3
分子量
503.03
CAS号
192581-24-1
运输条件
Room temperature in continental US; may vary elsewhere.