(+)-TK216 is an enantiomer of TK216 . TK216 is an orally active and potent E26 transformation specific (ETS) inhibitor.
体外研究
(+)-TK216 (compound 13; for 3 days) has an IC50>5 μM in SKES cells (Ewing Sarcoma cell line).
(+)-TK216 has T1/2s of 103.4 mins, 3.6 mins, 26.6 mins and 8.4 mins for human, rat, mouse, dog liver microsomes.
分子式
C19H15Cl2NO3
分子量
376.23
CAS号
1903783-77-6
运输条件
Room temperature in continental US; may vary elsewhere.