SK1-IN-1 is a potent sphingosine kinase 1 (SPHK1) inhibitor with an IC50 of 58 nM.
体内研究
SK1-IN-1 demonstrates significant improvement in the intrinsic clearance, particularly against human liver microsomes. SK1-IN-1 is selected for rat PK studies and demonstrates modest in oral bioavailability with acceptable half-lives in blood circulation.
分子式
C22H30N4O3
分子量
398.50
CAS号
1218816-71-7
运输条件
Room temperature in continental US; may vary elsewhere.