Tauro-Obeticholic acid 是牛磺酸的活性代谢物。Obeticholic Acid 是一种口服生物可利用的法尼样X受体 (FXR) 激动剂。
| 生物活性 |
Tauro-Obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an orally bioavailable farnesoid-X receptor (FXR) agonist. |
|---|---|
| 体外研究 |
Obeticholic acid is conjugated with taurine in the liver to form Tauro-obeticholic acid, which is secreted into bile. Microorganisms in the ileum and colon can deconjugate Tauro-obeticholic acid, converting it into the parent drug, which may then be reabsorbed or excreted in faeces. |
| 分子式 |
C28H49NO6S
|
| 分子量 |
527.76
|
| CAS号 |
863239-61-6
|
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
-20°C, protect from light, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen) |
纯度： ≥98%
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