CYM50260
目录号 : KM3950 CAS No. : 1355026-60-6 纯度 : 98%

CYM50260 是一种有效且选择性强的鞘氨醇-1-磷酸 4 受体 (S1P4-R) 激动剂,EC50 为 45 nM。CYM50260 对 S1P1-R,S1P2-R,S1P3-R 和 S1P5-R 无活性。

规格 价格 是否有货 数量
1mg
In-stock
5mg
In-stock
10mg
In-stock
50mg 询价 In-stock
100mg 询价 In-stock

Other Forms of Rapamycin:

KKL Med 的所有产品和服务仅用于科学研究,不能被用于人体,兽医,我们也不向个人提供产品和服务。
生物活性

CYM50260 is a potent and exquisitely selective sphingosine-1-phosphate 4 receptor (S1P4-R) agonist with an EC50 of 45 nM. CYM50260 displays no activity against S1P1-R, S1P2-R, S1P3-R and S1P5-R.

体外研究

CYM50260 (Compound 22aa) is a synthetic S1P4-R agonist. CYM50260 is found 3.5-fold more potent than the hit compound (HTS-hit).
CYM50260 suppresses the collagen-stimulated platelet aggregation, PDGF-AB secretion and sCD40L release. CYM50260 reduces the release of phosphorylated-HSP27 by collagen as well as the phosphorylation of HSP27.

分子式
C14H11Cl3FNO2
分子量
350.60
CAS号
1355026-60-6
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
在线客服
咨询热线
400-881-9290
关注微信公众号