AGL-2263 is an insulin receptor and insulin-like growth factor (IGF) receptor inhibitor.
IC50&Target
Insulin receptor.
体外研究
AGL-2263 (5 μM, for 1 h followed by insulin treatment for 24 h) inhibits IR and insulin could still induce phosphorylation of AKT and ERK1/2 after the IR inhibition.
Western Blot Analysis
Cell Line:
Granulosa cells.
Concentration:
5 μM.
Incubation Time:
For 1 h followed by insulin treatment for 24 h.
Result:
Insulin still induced phosphorylation of AKT and ERK1/2 after IR was inhibited by AGL2263.
分子量
322.27
CAS号
638213-98-6
运输条件
Room temperature in continental US; may vary elsewhere.