KKL 顾客使用本产品发表的 4 篇科研文献

ACP-105 is an orally available, selective amd potent androgen receptor modulator (SARM), with pEC₅₀s of 9.0 and 9.3 for AR wild type and T877A mutant, respectively.

ACP-105 is an orally available, selective amd potent androgen receptor modulator (SARM), with pEC₅₀s of 9.0 and 9.3 for AR wild type and T877A mutant, respectively. The half-lives of ACP-105 (compound 1) in human hepatocytes is measured and found to be 5.0 h.

ACP-105 enhances freezing in both sham-irradiated and irradiated mice (effect of ACP-105: F=5.44; p=0.028). For MAP-2 immunoreactivity in the cortex of sham-irradiated mice, there is a brain area×ACP-105 interaction (F=6.655; p=0.0027). While ACP-105 reduces MAP-2 immunoreactivity in the sensorymotor cortex, there is a trend towards increased MAP-2 immunoreactivity in the enthorhinal cortex.

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