GLX351322 is an inhibitor of NADPH oxidase 4, and inhibits hydrogen peroxide production from NOX4-overexpressing cells with an IC50 of 5 μM. GLX351322 shows weak activity against NOX2 in hPBMC cells (IC50, 40 μM).
体内研究
GLX351322 (3.8 mg/kg/day, p.o.) ameliorates HFD-induced hyperglycemia in mice.
分子式
C21H25N3O5S
分子量
431.51
CAS号
835598-94-2
运输条件
Room temperature in continental US; may vary elsewhere.