NIBR189 is a small molecule antagonist of the Epstein-Barr virus-induced gene 2 (EBI2; GPR183) receptor with IC50 of 16 nM(Binding) and 11 nM (Functional).
IC50 value: 16/11 nM(Binding/Functional IC50) [1]
Target: EBI2/GPR183 antagonist
NIBR189 is a potent and selective EBI2 antagonist with improved pharmacokinetic properties which will help to probe the physiological function of EBI2 in health and disease.
分子式
C21H21BrN2O3
分子量
429.31
CAS号
1599432-08-2
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Powder
-20°C
3 years
4°C
2 years
In solvent
-80°C
6 months
-20°C
1 month
溶解性数据
In Vitro:
DMSO : 50 mg/mL (116.47 mM; ultrasonic and warming and heat to 60°C)