MRS1845 is a selective store-operated calcium (SOC) channel inhibitor with an IC50 of 1.7 μM. MRS1845 is an ORAI1 inhibitor.
IC50&Target
Ca channel
体外研究
Treatment with MRS1845 (10 μM) virtually disrupts the effects of β-glycerophosphate on store-operated Ca entry (SOCE).
MRS1845 (10 μM) significantly decreases SOCE and virtually abolishes the increase of SOCE following placental growth factor (PlGF) treatment.
分子式
C21H22N2O6
分子量
398.41
CAS号
544478-19-5
运输条件
Room temperature in continental US; may vary elsewhere.