2-Ketoglutaric acid (Synonyms:α-酮戊二酸; Alpha-Ketoglutaric acid)
目录号 : KM20279 CAS No. : 328-50-7 纯度 : ≥95%

2-Ketoglutaric acid (Alpha-Ketoglutaric acid) 是 Krebs 循环中 ATP 或 GTP 产生的中间体。2-Ketoglutaric acid 还充当氮同化反应的主要碳骨架。2-Ketoglutaric acid 是酪氨酸酶 (tyrosinase) 的可逆抑制剂 (IC50=15 mM)。

规格 价格 是否有货 数量
500mg
In-stock
1g
In-stock
5g 询价 In-stock
10g 询价 In-stock

Other Forms of Rapamycin:

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生物活性

2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM).

体外研究

2-Ketoglutaric acid (Alpha-Ketoglutaric acid) has other physiological capabilities including reduction of ammonia level formed in the lung and general ammonia detoxification, protective role against lipid peroxidation and neuroprotective effect against cyanide poisoning.
2-Ketoglutaric acid acts as precursor for the synthesis of amino acids and nucleotides.

分子式
C5H6O5
分子量
146.10
CAS号
328-50-7
中文名称
α-酮戊二酸
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro: 

H2O : 50 mg/mL (342.23 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 6.8446 mL 34.2231 mL 68.4463 mL
5 mM 1.3689 mL 6.8446 mL 13.6893 mL
10 mM 0.6845 mL 3.4223 mL 6.8446 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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