Jasplakinolide 是一种有效的肌动蛋白聚合反应 (actin polymerization) 诱导剂，可以稳定先前存在的肌动蛋白丝。Jasplakinolide 与鬼笔环肽竞争性结合 F-肌动蛋白，Kd 值为 15 nM。Jasplakinolide 是一种来自海洋海绵 (marine sponge) 的天然环状肽，具有抗真菌和抗肿瘤活性。
| 生物活性 |
Jasplakinolide is a potent actin polymerization inducer and stabilizes pre-existing actin filaments. Jasplakinolide binds to F-actin competitively with phalloidin with a Kd of 15 nM. Jasplakinolide, a naturally occurring cyclic peptide from the marine sponge, has both fungicidal and anti-cancer activity. |
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| 体外研究 |
Jasplakinolide has an IC50 of 35 nM for the antiproliferative effect of jasplakinolide on PC3 prostate carcinoma cells. |
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| 分子式 |
C36H45N4O6Br
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| 分子量 |
709.67
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| CAS号 |
102396-24-7
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
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| 科研文献 |
客服小K 
客服小K
Data Sheet
