Urotensin II, mouse acetate is an endogenous ligand for the orphan G-protein-coupled receptor GPR14 or SENR. Urotensin II, mouse acetate is a potent vasoconstrictor. Urotensin II, mouse acetate plays a physiological role in the central nervous system.
体内研究
Urotensin II is a somatostatin-like cyclic peptide which functions as an arterial vasocontrictor, vasodilator, and bronchoconstriction mediator.
Urotensin II (0.1 nmol, 0.3 nmol, and 3 nmol; intracerebroventricular administration) induces anxiogenic-like behaviors in the elevated plus maze test and the hole-board test in mice in a dose-dependent manner.
Animal Model:
Male C57BL/6N mice (8 weeks old)
Dosage:
0.1 nmol, 0.3 nmol, and 3 nmol
Administration:
Intracerebroventricular (i.c.v.) administration
Result:
Decreased the amount of head dipping without significant alteration of the motor activity.
运输条件
Room temperature in continental US; may vary elsewhere.