Cridanimod is a potent progesterone receptor (PR) activator mediated through induction of IFNα and IFNβ expression. Cridanimod is a small-molecule immunomodulator and interferon inducer.
IC50&Target
PR, IFNα, IFNβ
体内研究
Cridanimod (IM; 1-6 mg; twice a week) has a significantly longer survival time. Cridanimod significant increases in IFNα and -β in cridanimod-treated mice in a dose-dependent manner.
Animal Model:
Athymic mice with hec50co cells
Dosage:
1, 3, 6 mg
Administration:
IM; twice a week
Result:
Had a significantly longer survival time.
分子式
C15H11NO3
分子量
253.26
CAS号
38609-97-1
运输条件
Room temperature in continental US; may vary elsewhere.