Schaftoside is a flavonoid found in a variety of Chinese herbal medicines, such as Eleusine indica. Schaftoside inhibits the expression of TLR4 and Myd88. Schaftoside also decreases Drp1 expression and phosphorylation, and reduces mitochondrial fission.
体外研究
Schaftoside inhibits three pro-inflammatory enzymatic activities: secretory phospholipase A2 (sPLA2), lipoxygenase (LOX), and cyclooxygenase 2 (COX-2). Schaftoside also inhibits mRNA and protein expressions of proinflammatory cytokines(IL-1β, TNF-α, and IL-6).
分子式
C26H28O14
分子量
564.49
CAS号
51938-32-0
中文名称
夏佛塔苷;夏佛托苷;夏佛托甙;夏佛塔甙
运输条件
Room temperature in continental US; may vary elsewhere.