Cannabisin F (0~15 μM; 1 hour; BV2 microglia cells) inhibits the phosphorylation of IκBα, p65, but enhances the expression of Nrf2 and HO-1.
Cannabisin F (0~15 μM; 24 hours; BV2 microglia cells) has no significant effect on cell survival, inhibits IL-6 and TNF-α production and their mRNA expression, inhibits the production of ROS and increases the expression of SIRT1.
Cell Viability Assay
Cell Line: |
BV2 microglia cells |
Concentration: |
0~15 µM |
Incubation Time: |
24 hours |
Result: |
Had no significant effect on cell survival.
|
Western Blot Analysis
Cell Line: |
BV2 microglia cells |
Concentration: |
0~15 µM |
Incubation Time: |
1 hour |
Result: |
Inhibited the phosphorylation of IκBα, p65, but enhanced the expression of Nrf2 and HO-1.
|