PAR-4 Agonist Peptide, amide (Synonyms:PAR-4-AP; AY-NH2)
目录号 : KM18190 CAS No. : 352017-71-1 纯度 : 98%

PAR-4 Agonist Peptide, amide (PAR-4-AP; AY-NH2) 是一种蛋白酶激活受体-4 (PAR-4) 激动剂,对 PAR-1 或 PAR-2 都没有作用,且其作用会被 PAR-4 拮抗剂阻断。

规格 价格 是否有货 数量
1mg
In-stock
5mg
In-stock
10mg
In-stock

Other Forms of Rapamycin:

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生物活性

PAR-4 Agonist Peptide, amide (PAR-4-AP; AY-NH2) is a proteinase-activated receptor-4 (PAR-4) agonist, which has no effect on either PAR-1 or PAR-2 and whose effects are blocked by a PAR-4 antagonist.

IC50&Target

PAR-4

体内研究

Compared with their BALB/cBy controls, SCID mice have a significantly greater abdominal response to colorectal distension (CRD) at the distension levels of 0.04 to 0.1 mL increasing the intensity of EMG response by 384% to 132%, respectively (P<0.01; P<0.01; P<0.01; P<0.001). PAR-4 activation effectively reverses this hypersensitivity (P<0.01, P<0.05; P<0.05; P<0.05) .

分子式
C34H48N8O7
分子量
680.79
CAS号
352017-71-1
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

科研文献
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DMSO母液配制方法 mg 药物溶于 μL DMSO溶液(母液浓度 mg/mL,

体内配方配制方法μL DMSO母液,加入 μL PEG300,混匀澄清后加入μL Tween 80,混匀澄清后加入 μL ddH2O,混匀澄清。

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