Liothyronine sodium 是一种有效的甲状腺激素，可以结合并激活 β1 甲状腺激素受体 (TRβ1)。
| 生物活性 |
Liothyronine sodium is an active form of thyroid hormone, which binds to β1 thyroid hormone receptor (TRβ1), and activates its activity. |
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| 体外研究 |
Liothyronine (T3, 100 nM) stimulates the proliferation of hepatocarcinema cells in which TRβ1 is overexpressed. Liothyronine binds to human β1 thyroid hormone receptor (hTRβ1), and change its conformation. Liothyronine promotes growth, induces differentiation and regualtes metabolic effects. |
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| 分子式 |
C15H11I3NNaO4
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| 分子量 |
672.96
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| CAS号 |
55-06-1
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| 中文名称 |
三碘代甲状腺素钠盐；碘塞罗宁钠
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
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| 溶解性数据 |
In Vitro:
0.1 M NaOH : 12.5 mg/mL (18.57 mM; ultrasonic and adjust pH to 11 with NaOH) DMSO : 5.56 mg/mL (8.26 mM; ultrasonic and warming and heat to 60°C) H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 |
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| 科研文献 |
纯度： 98%
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