Apraglutide (FE 203799; 5 mg/kg/dose, subcutaneously, twice on days 0 and 4 postsurgery) treated piglets are healthy, have significant lower fecal fat and energy losses and exhibite intestinal lengthening, greater small-intestinal weight, longer villus height, and greater crypt depth on day 7.
Animal Model: |
NewbornDuroc piglets, 2–5 days old and weighing between 2-2.6 kg. |
Dosage: |
5 mg/kg/dose. |
Administration: |
Subcutaneously, twice on days 0 and 4 postsurgery. |
Result: |
On day 7, treated piglets were healthy, had significant lower fecal fat and energy losses and exhibited intestinal lengthening, greater small-intestinal weight, longer villus height, and greater crypt depth. |