Alminoprofen (Synonyms:EB-382)
目录号 : KM17560 CAS No. : 39718-89-3 纯度 : 98%

Alminoprofen 是苯丙酸类非甾体抗炎药 (NSAID)。Alminoprofen 同时具有抑制分泌磷脂酶A2 (sPLA2) 活性和抗环氧化酶 (COX-2) 的活性。

规格 价格 是否有货 数量
10mg
In-stock
50mg 询价 In-stock
100mg 询价 In-stock

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生物活性

Alminoprofen (EB-382) is a nonsteroidal anti-inflammatory drug (NSAID) of the phenylpropionic acid class. Alminoprofen possesses a dual anti-inflammatory action, by inhibiting both secretory phospholipase A2 (sPLA2) and COX-2.

体外研究

Alminoprofen possesses a dual anti-inflammatory action, by inhibiting both sPLA2 but also COX-2. Alminoprofen (from 0 to 50 μM) induces a dose-related inhibitory response on thelevels of PGE2 formed by the CRL-1517 cell line.

体内研究

Alminoprofen (100-300 mg/kg; p.o.) exerts an anti-inflammatory activity.

Animal Model: Groups of Wistar Rats (Oedema of the paw)
Dosage: 100 mg/kg
Administration: P.o.
Result: Exerted a statistically significant dose-dependent antagonist action lasting throughout the 2-hr observation period.
分子式
C13H17NO2
分子量
219.28
CAS号
39718-89-3
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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