Adalimumab is a human monoclonal IgG1 antibody targeting tumour necrosis factor α (TNF-α).
IC50&Target
TNF-α
体外研究
Treatment of HUVECs with Adalimumab for up to 12 hours shows no adverse effect on their cell viability, even with a 10-fold higher concentration of Adalimumab than used in this study.
体内研究
The elimination half-life (t1/2) of Adalimumab is long (~20 days). The enriched fluorescent-labelled adalimumab is observed mainly in major Oil red O-positive lesions documenting good tissue penetration of the drug into the atherosclerotic plaque, without background fluorescence of the vessel wall after vehicle control injection into hypercholesterolemic Ldlr mice.
分子式
C20H22N2O7S
分子量
145425.42
CAS号
331731-18-1
中文名称
阿达木单抗;阿达莫单抗
运输条件
Shipping with dry ice.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.