Adalimumab is a human monoclonal IgG1 antibody targeting tumour necrosis factor α (TNF-α).
IC50&Target
TNF-α
体外研究
Treatment of HUVECs with Adalimumab for up to 12 hours shows no adverse effect on their cell viability, even with a 10-fold higher concentration of Adalimumab than used in this study.
体内研究
The elimination half-life (t1/2) of Adalimumab is long (~20 days). The enriched fluorescent-labelled adalimumab is observed mainly in major Oil red O-positive lesions documenting good tissue penetration of the drug into the atherosclerotic plaque, without background fluorescence of the vessel wall after vehicle control injection into hypercholesterolemic Ldlr mice.
分子量
145.43 kDa
CAS号
331731-18-1
中文名称
阿达木单抗;阿达莫单抗
运输条件
Shipping with dry ice.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
种属
Human
同种型
Human IgG1 kappa
Accession号
P01375
应用
ELISA, FACS, Functional assay
基因 ID
7124 [NCBI]
复溶方法
The product can be reconstituted/diluted with sterile PBS or saline.