Bevacizumab (Synonyms:Anti-Human VEGF, Humanized Antibody (PBS))
目录号 : KM17048 CAS No. : 216974-75-3 纯度 : 98%

Bevacizumab 是一种人源化的单克隆抗体,高亲和力且特异性地与所有 VEGF-A 结合。

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1mg
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5mg
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25mg 询价 In-stock
50mg 询价 In-stock

Other Forms of Rapamycin:

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生物活性

Bevacizumab, a humanized monoclonal antibody, specifically binds to all VEGF-A isoforms with high affinity.

体外研究

Bevacizumab, a humanized monoclonal antibody, specifically binds to all VEGF-A isoforms with high affinity, and inhibits its interaction with VEGFR-1 and VEGFR-2. Experimental analysis shows that the EC50 of Bevacizumab to bind VEGF analyzed by ELISA is 0.18 μg/mL. Binding kinetics assays show similar results that Bevacizumab inhibits the VEGF-induced proliferation of HUVEC with an IC50 value of 0.047±0.0081 μg/mL.

体内研究

It is demonstrated that the subconjunctival administration of FD006 and Bevacizumab can significantly inhibit CoNV in NaOH cauterized rats compared with the control group (p < 0.01).

分子量
146.56 kDa
CAS号
216974-75-3
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

临床试验
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