Bevacizumab 是一种人源化的单克隆抗体，高亲和力且特异性地与所有 VEGF-A 结合。
| 生物活性 |
Bevacizumab, a humanized monoclonal antibody, specifically binds to all VEGF-A isoforms with high affinity. |
|---|---|
| 体外研究 |
Bevacizumab, a humanized monoclonal antibody, specifically binds to all VEGF-A isoforms with high affinity, and inhibits its interaction with VEGFR-1 and VEGFR-2. Experimental analysis shows that the EC50 of Bevacizumab to bind VEGF analyzed by ELISA is 0.18 μg/mL. Binding kinetics assays show similar results that Bevacizumab inhibits the VEGF-induced proliferation of HUVEC with an IC50 value of 0.047±0.0081 μg/mL. |
| 体内研究 |
It is demonstrated that the subconjunctival administration of FD006 and Bevacizumab can significantly inhibit CoNV in NaOH cauterized rats compared with the control group (p < 0.01).
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| 分子式 |
C10H6O3
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| CAS号 |
216974-75-3
|
| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
| 临床试验 |
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| 科研文献 |
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纯度： 98%
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