Bismuth Subsalicylate is a potent and orally active antacid and anti-diarrheal agent. Bismuth Subsalicylate reduces inflammation/irritation of stomach and intestinal lining through inhibition of prostaglandin synthesis in vivo. Bismuth Subsalicylate is widely used for the research of diarrheal disorders, including indigestion, diarrhoea, nausea, et al.
体内研究
In the gastrointestinal tract, Bismuth Subsalicylate can be converted to salicylic acid and insoluble bismuth salts. Salicylic acid reduces inflammation/irritation of stomach and intestinal lining through inhibition of prostaglandin G/H synthase 1/2. Bismuth Subsalicylate (oral gavage; 100 mg/kg-350 mg/kg) significantly decreases castor oil-induced movement of a charcoal test meal along the small intestine of the mouse and rat and also decreases both the fecal output (dry or wet weight) and the frequency of diarrhea in mice.
分子式
C7H6BiO4
分子量
362.09
CAS号
14882-18-9
中文名称
次水杨酸铋;碱式水杨酸铋;次柳酸铋水杨酸铋;次柳酸铋;亚水杨酸铋
运输条件
Room temperature in continental US; may vary elsewhere.