Autocamtide 2 - CAS:129198-88-5

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Autocamtide 2 (Synonyms:Autocamtide II)

目录号 : KM15081 CAS No. : 129198-88-5 纯度 : 98%

Data Sheet 产品使用指南

Autocamtide 2是钙/钙调蛋白依赖的蛋白激酶II (CaMKII)的高选择性肽底物。它可以用于测定CaMKII的活力。

规格	价格	是否有货
1mg		In-stock
5mg		In-stock
10mg	询价	In-stock
50mg	询价	In-stock

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Other Forms of Rapamycin:

Ginkgolide J In-stock
Ginkgolide K In-stock
THK-5470 In-stock
NH-3 In-stock
Velufenacin In-stock

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生物活性

Autocamtide 2 is a highly selective peptide substrate of calcium/calmodulin-dependent protein kinase II (CaMKII). It can be used in the CaMKII activity assay.

体外研究

The Ca/calmodulin dependent protein kinases (CaMKs) are multifunctional serine/threonine kinases whose activity are regulated through Ca signaling. It is multifunctional best known for its critical role in learning and memory. Recent studies demonstrates that high levels of different isoform of CaMK, especially for CaMKII, expresses in several cancers such as lung, breast, prostate and colon cancer. CaMKII phosphorylates nearly 40 different proteins, including enzymes, ion channels, kinases, and transcription factors and plays a critical role in the regulation of proliferation, differentiation and survival of various cancer cells.

分子式

C₆₅H₁₁₈N₂₂O₂₀

分子量

1527.77

CAS号

129198-88-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据

In Vitro:

H₂O : 20 mg/mL (13.09 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	0.6545 mL	3.2727 mL	6.5455 mL
5 mM	0.1309 mL	0.6545 mL	1.3091 mL
10 mM	0.0655 mL	0.3273 mL	0.6545 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

纯度： 98%