Ciclesonide (RPR251526) is a glucocorticoid with an potent anti-inflammatory activity. Ciclesonide can be used for asthma research.
体外研究
Ciclesonide, the parent compound, undergoes hydrolysis by ester cleavage at the C21 position to the active metabolite, desisobutyryl-ciclesonide (des-CIC), followed by reversible formation of fatty acid esters within the lung cells. Ciclesonide (5 μM) is rapidly hydrolyzed by normal human bronchial epithelial (NHBE) cells (approximately 30% conversion at 4h), with almost complete conversion by 24 h.
分子式
C32H44O7
分子量
540.69
CAS号
126544-47-6
中文名称
环索奈德
运输条件
Room temperature in continental US; may vary elsewhere.